1. Cytokines are local regulators, which of the following is not true of them?
1) Produced by TH cells or infected cells
2) They bind to cell surface receptors
3) Interleukins are antiviral proteins
4) Interferons are 3 types
2. Find the odd man out with respect to their chemical nature?
1) Epinephrine 2) Nor epinephrine
3) Thyroxine 4) Melatonin
3. Which of the following is not a complex protein hormone?
1) Prolactin 2) TSH 3) FSH 4) LH
4. Osmoreceptors of hypothalamus regulate the secretion of
1) ACTH 2) Prolactin 3) ADH 4) Oxytocin
5. IGFs are not concerned with
1) Cell division 2) Cell differentiation
3) Acceleration of protein synthesis
4) Acceleration of catabolism of proteins
6. Which of the following does not belong to hypophysis cerebri?
1) Melatonin 2) Oxytocin 3) Prolactin 4) hGH
7. Hypersecretion of hGH during childhood causes
1) Gigantism 2) Acromegaly 3) Pituitary dwarf 4) Midget
8. Which of the following is not true of acromegaly?
1) Disproportionate gigantism 2) Gorilla like appearance
3) Child like appearance
4) Enlargement of eyelids, lips and tongue
9. A Patient of diabetes insipidus will experience
1) Dehydration 2) Thirst
3) Excretion of large quantities of urine
4) All of the above
10. The funtion not performed by thyroid hormones is
1) Stimulation of erythropoiesis
2) Production of ATP
3) Maintenance of water and electrolyte balance
4) Sleep - wake cycle regulation
11. Match the following.
List-I List-II
I) Antagonistic to A) T3, T4 hormones MSH
II) ATP Production B) TCT hormone
III) Inhibiting the action C) Thymosins of Osteoclasts
IV) Congenital D) Melatonin hypothyroidism
V) Activating vitamin D E) Collip's hormone
F) Low IQ and mute
I II III IV V I II III IV V
1) D B A F E 2) D A B F E
3) E A B D C 4) C A B D F
12. Thymus gland is maximum sized at
1) Adulthood 2) Old age 3) Puberty 4) Childhood
13. Which is not true of cortisol function?
1) Generates anti-inflammatory effect
2) Stress combat hormone
3) Lipolytic and protelytic hormone
4) Maintains electrolyte and body fluid volume
14. Which of the following is not a symptom of Addison's disease?
1) Loss of weight 2) Low blood pressure
3) Decreased cardiac output
4) Redistribution of body fat
15. Read the following.
A) Tumor is adrenal cortex or pituitary gland can cause Cushings syndrome
B) Poor wound healing and flushed facial skin are signs of Cushing's syndrome
C) Congenital adrenal hyperplasia can lead to masculunization of a female The correct statements are
1) A, B 2) B, C 3) A, C 4) All
16. Liver cells are acted upon by
1) Insulin 2) Glucagon 3) Adrenaline 4) All
17. Read the following about hyperinulinism and arrange them properly from starting.
A) Secretion of epinephrine and glucagon
B) Hypoglycemia C) Increased heart rate
D) Anxiety, sweating E) Convulsions
F) Weakness and hunger G) Unconsciousness and shock
1) F - A - D - B - E - G - C 2) A - B - C - D - F - G - E
3) B - A - C - D - F - E - G 4) B - D - C - A - E - F - G
18. Hypogonadism can be caused due to shortage of
1) LH 2) FSH 3) Testosterone 4) All of the above
19. Identify the wrongly matched pair.
1) Erythropoietin - peptide hormone
2) Dihydroxy chole calciferol - active form of vitamin D
3) Pituicytes - special neuroglial cells
4) Eunuchoidism - failure of oestrogen secretion
20. When two hormones together show greater effect than sum of each hormone alone, as they complement each other, it is
1) Antagonistic effect 2) Positive feedback effect
3) Synergic effect 4) Permissive effect
21. In the mechanism of action of hormone epinephrine on hepatocytes the first messenger is
1) c-AMP 2) GTP 3) Adenylate cyclase 4) Epinephrine
22. Graves disease is caused due to
1) Hyposecretion of thyroid gland 2) Hypersecretion thyroid gland
3) Hypersecretion of adrenal gland 4) Hyposecretion of adrenal gland
23. The amino acid tryptophan is the precursor for the synthesis of
1) Thyroxine and triiodothyronine 2) Estrogen and progesterone
3) Epinephrine and norepinephrine 4) Melatonin and serotonin
24. Calcium level is not regulated by
1) Vitamin D 2) Thyroxine 3) Calcitonin 4) Collip's hormone
25. Which of the following hormones is not a steroid?
1) Vasopressin 2) Testosterone 3) Androgen 4) Aldosterone
26. Accidental damage to pituitary stalk will cause all except
1) Diabetes mellitus 2) Diabetes insipidus 3) Hypothyrodism 4) Addison's disease
27. Which one of the following hormones though synthyesized else where is stored and released by the master gland?
1) Antidiuretic hormone 2) Luteinizing hormone
3) Prolactin 4) Melanocyte stimulating hormone
28. Which one of the following hormone is not involved in sugar metabolism?
1) Cortisone 2) Aldosterone 3) Insulin 4) Glucagon
29. Chemical signal that has both endocrine and neural roles is
1) Calcitonin 2) Epinephrine 3) Cortisol 4) Melatonin
30. Select the answer which correctly matches the endocrine gland with the hormone it secretes and its function/deficiency symptoms. 
31. With reference to the pituitary which of the following statements is true?
1) Neurohypophysis secretes vasopressin and oxytocin
2) Neurohypophysis secretes TSH and STH
3) Neurohypophysis collects and stores vasopressin and oxytocin
4) Adenohypophysis secretes vaso pressin and oxytocin
32. Which of the following hormones is a steroid?
1) Oestrogen 2) Insulin 3) Glucagon 4) Thyroxine
33. Endemic goitre is a state of
1) Increased thyroid function 2) Normal thyroid function
3) Decreased thyroid function 4) Moderate thyroid function
34. Name the condition when the concentration of ketone bodies increase in urine.
1) Acromegaly 2) Diabetes mellitus
3) Turner's syndrome 4) Diabetes insipidus
35. Goiter can occur as a consequence of all the following except.
1) Grave's disease 2) Excessive intake of exogeneous thyroxine
3) Iodine deficiency 4) Pituitary adenoma
36. Damage of thymus in a child may lead to
1) Loss of cell mediated immunity
2) Loss of antibody mediated immunity
3) A reduction in the amount of plasma proteins
4) A reduction in the haemoglobin content in blood
37. Secretion of mineralo corticoids is under the control of
1) FSH 2) TSH 3) ACTH 4) ADH
38. Master gland pituitary has a non - functional part in humans, it is
1) Anterior pituitary 2) Pars intermedia
3) Neurohypophysis 4) Pars nervosa
39. Which of the following is not correct for the effect of parathormone?
1) It encourages the activity of osteoclasts
2) It lowers blood Ca2+ level
3) In its absence, body shivers due to constant muscle contraction
4) It stimulates absorption of Ca2+ by intestinal mucosa
40. Somatostatin is produced in
1) Adenohypophysis 2) Neurohypophysis
3) Pineal gland 4) Basal part of diencephalon
41. The 24 hours (Diurnal) rhythm of our body such as the sleep - wake cycle is regulated by the hormone
1) Calcitonin 2) Prolactin 3) Adrenaline 4) Melatonin
42. Which of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in nucleus)?
1) thyroxine, insulin 2) somatostatin, oxytocin
3) cortisol, testosterone 4) insulin, glucagon
43. Which hormone is secreted more in dark condition?
1) Insulin 2) Melatonin 3) Thyroxine 4) Adrenaline
44. Hyperglycemia is induced by all the following hormones except
1) Glucagon 2) Thyroxine 3) Aldosterone 4) Glucocorticoid
Answers: 1-3; 2-4; 3-1; 4-3; 5-4; 6-1; 7-1; 8-3; 9-4; 10-4; 11-2; 12-3; 13-4; 14-4; 15-4; 16-4; 17-3; 18-4; 19-4; 20-3; 21-4; 22-2; 23-4; 24-2; 25-1; 26-1; 27-1; 28-2; 29-2; 30-1; 31-3; 32-1; 33-3; 34-2; 35-2; 36-1; 37-3; 38-2; 39-2; 40-4; 41-4; 42-3; 43-2; 44-3.
